1. Primary Surgical Therapy for Osteonecrosis of the Jaw Secondary to Bisphosphonate Therapy 
Deepak Kademani, DMD, MD, Sreenivas Koka, DDS, MS, PhD, Martha Q. Lacy, MD, S. Vincent Rajkumar, MD 
Mayo Clinic Proceedings 
Volume 81, Issue 8, Pages (August 2006)
DOI: /
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

2. FIGURE 1
Case 1. Area of ulcerated bone exposure with overlying granulation tissue in the right posterior mandible secondary to bisphosphonate therapy and an uncomplicated dental extraction 6 months previously.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

3. FIGURE 2
Case 1. Limited surgical exposure delineating the area of bone sequestration and poorly healed dental extraction site. This area was meticulously débrided to limit surgical trauma.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

4. FIGURE 3
Case 1. After sufficient subperiosteal-releasing incisions were made to facilitate closure, the soft tissue overlying the bony defect was closed in a tension-free fashion. Complete soft tissue healing ensued without incident.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

5. FIGURE 4
Case 1. Site of osteonecrosis of the jaw 4 months after primary surgical management.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions

6. FIGURE 5
Area of established osteonecrosis in the left retromolar trigone of the mandible with a large area of mucosal dehiscence. This patient was treated with local débridement and closure with a buccal fat pad rotational flap that was allowed to mucosalize in the oral cavity.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 2006 Mayo Foundation for Medical Education and Research Terms and Conditions