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IVUS-XPL Trial design: Patients undergoing drug-eluting stent implantation for long coronary lesions were randomized to IVUS-guided PCI (n = 700) vs. angiography-guided.

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Presentation on theme: "IVUS-XPL Trial design: Patients undergoing drug-eluting stent implantation for long coronary lesions were randomized to IVUS-guided PCI (n = 700) vs. angiography-guided."— Presentation transcript:

1 IVUS-XPL Trial design: Patients undergoing drug-eluting stent implantation for long coronary lesions were randomized to IVUS-guided PCI (n = 700) vs. angiography-guided PCI (n = 700). Results (p = 0.007) Cardiac death, MI, or target lesion revascularization: 2.9% of the IVUS-guided PCI group vs. 5.8% of the angiography-guided PCI group (p = 0.007) Target lesion revascularization: 2.5% with IVUS-guided PCI vs. 5.0% with angiography-guided PCI (p = 0.02) Definite/probable stent thrombosis: 0.3% with IVUS-guided PCI vs. 0.3% with angiography-guided PCI 5.8 % 2.9 Conclusions Among individuals undergoing PCI for long coronary lesions, IVUS-guided PCI was superior at reducing adverse cardiac events compared with angiography-guided PCI Benefit was due to a reduction in target lesion revascularization with the use of IVUS IVUS-guided PCI Angiography-guided PCI Hong SJ, et al. JAMA 2015;314:


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