1. Why girls are all there and boys are missing parts!!
4.3 Complex Inheritance
Why girls are all there and boys are missing parts!!

2. Warm-up Essential Question
What are the chromosomes that determine your sex?
Essential Question
How are traits passed on the X-Chromosome through generations?

3. Inherited Diseases- Recessive
Albinism- absence of melanin pigment
Male pattern Baldness
Hemophilia – the inability for the blood to clot correctly
Red-Green color blindness

4. Inherited Diseases- dominant
Huntington’s Disease- affects nervous system in people years old.
Achondroplasia- most common form of Dwarfism. Shortened arms, legs body trunk but normal width

5. Sex-Linked traits A gene found on the X chromosomes
Because, males only have one X chromosome, they have a much greater chance of the gene expressed. Females would have to be homozygous recessive in order to have the gene expressed
Carrier: someone who has a gene that is not expressed
Ex: colorblindness

6. Let’s try it!

8. Pedigree
a pedigree is a diagram showing genetic relationships between members of a family
By charting diseases and other traits through a family, we can see patterns
These patterns can tell us about dominant/recessive and whether it is sex linked
Note that a girl with a dominant sex link trait CAN’T be a carrier!

10. Practice! Fill out the genotypes of the family

11. Blood Typing Co-dominance
3 different alleles: A, B, O
Create 4 different blood types: A, AB, B, O
Type O is recessive (basically a lack of A or B alleles), all others can “share”
Each parent “donates” one blood type allele to offspring
Create antigens on each red blood cell – how your body knows it’s your blood

12. Which alleles are there?
Blood type A, could be: _____ or _____
Blood type B, could be ______ or _____
Blood type AB: ______
Blood type O: _______

13. Blood Typing Rh factor – Rhesus (monkey) factor
Rh+ dominant, Rh- recessive
Each parent donates one to offspring, either + or -

14. Universal donor: type O
No antigens present
Universal recipient: AB+
Already has antigens for both, will not create antibodies and fight off any type

16. Your Family tree Pick 6 traits
Record your phenotype and predicted genotype for each trait
Research this trait as far back as you can
Create 6 pedigree charts – one for each trait
Due Friday November 2