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Volume 134, Issue 3, Pages (March 2008)

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1 Volume 134, Issue 3, Pages 706-715 (March 2008)
Immunoglobulin G4–Associated Cholangitis: Clinical Profile and Response to Therapy  Amaar Ghazale, Suresh T. Chari, Lizhi Zhang, Thomas C. Smyrk, Naoki Takahashi, Michael J. Levy, Mark D. Topazian, Jonathan E. Clain, Randall K. Pearson, Bret T. Petersen, Santhi Swaroop Vege, Keith Lindor, Michael B. Farnell  Gastroenterology  Volume 134, Issue 3, Pages (March 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 IgG4-associated sclerosing cholangitis with intrahepatic strictures mimicking PSC (A) before treatment, and (B) after 12 weeks of steroid therapy. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Flowchart of study patients (n = 53) according to treatment groups. *Relapse rates did not differ between the surgery and steroid groups (P = .1, NS). The time to relapse was longer in the surgery group (P = .03); however, the range was wide. †Serologic relapse occurred in only 1 patient in this group (overall, 3 patients had only serologic relapse [without a biochemical relapse]). AZA, azathioprine; MM, mycophenolate mofetil. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 Kaplan–Meier curve of relapse-free survival in patients with distal (intrapancreatic) strictures only vs patients with any proximal strictures (proximal extrahepatic, intrahepatic, or both). —, Distal only (n = 27); - - -, any proximal (n = 26). *P = .02. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

5 Figure 4 Algorithm for the diagnosis and management of suspected IAC.
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions


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