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Effect of distal graft anastomosis site on retrograde perfusion and flow patterns of native coronary vasculature  Lin-rui Guo, MD, David A Steinman, PhD,

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Presentation on theme: "Effect of distal graft anastomosis site on retrograde perfusion and flow patterns of native coronary vasculature  Lin-rui Guo, MD, David A Steinman, PhD,"— Presentation transcript:

1 Effect of distal graft anastomosis site on retrograde perfusion and flow patterns of native coronary vasculature  Lin-rui Guo, MD, David A Steinman, PhD, Byung C Moon, Wan-Kei Wan, PhD, Richard J Millsap, BS  The Annals of Thoracic Surgery  Volume 72, Issue 3, Pages (September 2001) DOI: /S (01)

2 Fig 1 (a) Schematic of the downstream and upstream graft configurations illustrating the anticipated directions of blood flow. LAD = left anterior descending coronary (host) artery; LIMA = left internal mammary artery graft. (b) Corresponding finite element models, identifying the flow rate (Q) variables. The Annals of Thoracic Surgery  , DOI: ( /S (01) )

3 Fig 2 Experimental setup for dye studies, shown with the upstream graft model (not to scale). The Annals of Thoracic Surgery  , DOI: ( /S (01) )

4 Fig 3 The effect of graft placement on computed center-plane velocities for the case of a fully occluded stenosis. Computational fluid dynamic (CFD) studies with steady flow. (a) downstream model; (b) upstream model; (c) native model. Pulsatile flow at peak flow rate (see inset flow waveform in f): (d) downstream model; (e) upstream model; (f) native model. Velocity magnitude (in cm/s) is indicated by both color and vector length; flow direction is indicated by vector orientation. Note the different contour levels and vector lengths used for the steady (a–c) and pulsatile (d–f) velocity fields. The Annals of Thoracic Surgery  , DOI: ( /S (01) )

5 Fig 4 Effect of stenosis inflow on center-plane velocity field of the downstream model. Computational fluid dynamic (CFD) studies with steady flow: (a) stenosis inflow = 10%; (b) stenosis inflow =25%; (c) stenosis inflow = 40%. In vitro dye: (d) stenosis inflow = 10%; (e) stenosis inflow = 25%; (f) stenosis inflow = 40%. Refer to Fig 3c for the contour levels and vector lengths used for (a)–(c). Images of the dye studies were acquired shortly after dye injection had ceased. The Annals of Thoracic Surgery  , DOI: ( /S (01) )


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