1. On vascular calcification and plasma levels of pyrophosphate
Ricardo Villa-Bellosta 
Kidney International 
Volume 87, Issue 1, (January 2015)
DOI: /ki
Copyright © 2015 International Society of Nephrology Terms and Conditions

2. Figure 1
Schematic representation of the role of systemic ATP and local PPi synthesis in the prevention of vascular calcification. Pyrophosphate (PPi) is an inhibitor of calcium–phosphate deposition (CPD), which is synthesized by hydrolysis of extracellular ATP via ectonucleotide pyrophosphatase phosphodiesterase 1 (eNPP1). (a) Aorta allograft of wild-type mice (left) or Enpp1−/− mice (right) transplanted into wild-type (WT) mice. (b) Aorta allograft of WT mice (left) or Enpp1−/− mice (right) in Enpp1−/− mice. VSMC, vascular smooth muscle cell.
Kidney International  , DOI: ( /ki )
Copyright © 2015 International Society of Nephrology Terms and Conditions