1. Leukocyte Effects of C5a-Receptor Blockade During Simulated Extracorporeal Circulation 
Christine S. Rinder, MD, Michael J. Smith, PhD, Henry M. Rinder, MD, Daniel N. Cortright, PhD, Robbin M. Brodbeck, PhD, James E. Krause, PhD, Brian R. Smith, MD 
The Annals of Thoracic Surgery 
Volume 83, Issue 1, Pages (January 2007)
DOI: /j.athoracsur
Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Leukocyte CD11b upregulation during simulated extracorporeal circulation. CD11b expression was measured on neutrophils (PMN) at the time points shown (expressed as a percentage of baseline). The mean ± standard error of the mean from five experiments performed after addition of the C5aR antagonist (♦) and four control experiments using diluent (▴) are shown. The C5aR antagonist significantly inhibited neutrophil CD11b upregulation (p = 0.003).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Leukocyte–platelet conjugates during simulated extracorporeal circulation. The percentage of neutrophil (PMN)–platelet (A) and monocyte–platelet (B) conjugates is expressed as a percentage of baseline. The mean ± standard error of the mean from five experiments performed after addition of the C5aR antagonist (♦) and four control experiments using diluent (▴) are shown. The C5aR antagonist significantly inhibited both neutrophil–platelet (A) and monocyte–platelet conjugate formation (B; p < for both).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions