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Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis 

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Presentation on theme: "Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis "— Presentation transcript:

1 Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis  M.I. Queipo-Ortuño, J.D. Colmenero, M.J. Bravo, M.A. García-Ordoñez, P. Morata  Clinical Microbiology and Infection  Volume 14, Issue 12, Pages (December 2008) DOI: /j x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 Area under the receiver operating characteristic curves (ROC AUC) for testing the ability of the LC Q-PCR to distinguish active from inactive brucellosis. ROC curves were constructed by plotting sensitivity and 1-specificity corresponding to each cut-off value for the Brucella DNA load. (a) Considering a cut-off of 5 × 103 copies/mL. (b) Considering a cut-off of 2.2 × 105 copies/mL to achieve a specificity of 100%. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions


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