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Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents    Clinical Microbiology and Infection  Volume.

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Presentation on theme: "Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents    Clinical Microbiology and Infection  Volume."— Presentation transcript:

1 Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents  Clinical Microbiology and Infection  Volume 6, Issue 9, Pages (September 2000) DOI: /j x Copyright © Terms and Conditions

2 Figure 1 Hypothetical distribution of MICs among strains of bacteria isolated from infected patients, classified as clinically susceptible (fully or borderline), intermediate or resistant, and microbiologically susceptible or low-level, moderately or high-level resistant. Clinical Microbiology and Infection 2000 6, DOI: ( /j x) Copyright © Terms and Conditions

3 Figure 2 Interpretation of an isobologram for two antibiotics A and B in a checkerboard titration. Clinical Microbiology and Infection 2000 6, DOI: ( /j x) Copyright © Terms and Conditions

4 Figure 3 Hypothetical time-kill curves for two antibiotics A and B acting on a bacterial culture alone and in combination demonstrating synergism (the difference in Δ log CFU/h for the combination being ≥ 2-fold that of the most active component). Clinical Microbiology and Infection 2000 6, DOI: ( /j x) Copyright © Terms and Conditions


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