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Volume 57, Issue 1, Pages (January 2000)

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Presentation on theme: "Volume 57, Issue 1, Pages (January 2000)"— Presentation transcript:

1 Volume 57, Issue 1, Pages 224-231 (January 2000)
Renal hemodynamics and pharmacokinetics of bosentan with and without cyclosporine A  Isabelle Binet, M.D., Andreas Wallnöfer, Cornelia Weber, Richard Jones, Gilbert Thiel  Kidney International  Volume 57, Issue 1, Pages (January 2000) DOI: /j x Copyright © 2000 International Society of Nephrology Terms and Conditions

2 Figure 1 Study design. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

3 Figure 2 Systolic/diastolic blood pressure. Mean results (± SEM) of hourly blood pressure measurements during clearance assessment after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

4 Figure 3 Glomerular filtration rate. Mean results (± SEM) of hourly inulin clearance after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

5 Figure 4 Renal plasma flow. Mean results (± SEM) of hourly PAH clearance after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions


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