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Sensory processing: Signal selection by cortical feedback

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1 Sensory processing: Signal selection by cortical feedback
Andrew J King  Current Biology  Volume 7, Issue 2, Pages R85-R88 (February 1997) DOI: /S (06)

2 Figure 1 The principal ascending and descending auditory pathways associated with the cochlea on one side of the body. The major auditory centres actually consist of a number of anatomically and functionally distinct subdivisions. Many of the arrows therefore represent several parallel pathways interconnecting different regions within these centres. This simplified view of the auditory system also ignores other smaller projections. Current Biology 1997 7, R85-R88DOI: ( /S (06) )

3 Figure 2 View of the brain of the mustached bat from the left side. The FM–FM or range-finding cortical field is located slightly dorsal and anterior to the primary auditory cortex (AI). The FM–FM area has reciprocal ascending and descending connections with the medial geniculate nucleus (MGN) in the thalamus. It also sends a descending projection to the inferior colliculus (IC) in the midbrain, which, in turn, projects up to the MGN. (b) Schematic response of a neuron in the IC to pairs of FM sounds simulating the FM components of the bat's biosonar pulse and its echo. The response varies with echo delay. Electrical stimulation of cortical neurons with matched best delays increases the response of the IC neuron and sharpens its delay tuning, whereas cortical inactivation by injection of local anaesthetic has the opposite effect. Current Biology 1997 7, R85-R88DOI: ( /S (06) )


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