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Published byFrédéric Brunet Modified over 5 years ago
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Isolation of a cDNA Representing the Fanconi Anemia Complementation Group E Gene
Johan P. de Winter, France Léveillé, Carola G.M. van Berkel, Martin A. Rooimans, Laura van der Weel, Jurgen Steltenpool, Ilja Demuth, Neil V. Morgan, Noa Alon, Lucine Bosnoyan-Collins, Jeff Lightfoot, Peter A. Leegwater, Quinten Waisfisz, Kenshi Komatsu, Fré Arwert, Jan C. Pronk, Christopher G. Mathew, Martin Digweed, Manuel Buchwald, Hans Joenje The American Journal of Human Genetics Volume 67, Issue 5, Pages (November 2000) DOI: /S (07) Copyright © 2000 The American Society of Human Genetics Terms and Conditions
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Figure 1 Complementation of MMC hypersensitivity in FA-E lymphoblastoid cell line EUFA410, and FANCE protein sequence. a, MMC hypersensitivity of FA-E cell line EUFA410 is corrected after transfection of FANCE cDNA clone 10. HSC93, wild type control. b, Amino acid sequence of the FANCE protein. Nuclear localization signals as predicted by PSORT II (Nakai and Horton, 1999) are shown in bold and underlined. The American Journal of Human Genetics , DOI: ( /S (07) ) Copyright © 2000 The American Society of Human Genetics Terms and Conditions
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