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Pulmonary flow study predicts survival in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries  Jiaquan Zhu,

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Presentation on theme: "Pulmonary flow study predicts survival in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries  Jiaquan Zhu,"— Presentation transcript:

1 Pulmonary flow study predicts survival in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries  Jiaquan Zhu, MD, PhD, James Meza, MD, Atsuko Kato, MD, Arezou Saedi, MD, Devin Chetan, MD, Rachel Parker, BScH, Christopher A. Caldarone, MD, Brian W. McCrindle, MD, MPH, Glen S. Van Arsdell, MD, Osami Honjo, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 152, Issue 6, Pages e1 (December 2016) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Flowchart of surgical strategy. The number in the bracket represents number of deaths. PA, Pulmonary atresia; VSD, ventricular septal defect; MAPCAs, major aortopulmonary collateral arteries. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Relationship between ventricular septal defect (VSD) status and mean pulmonary artery pressure (PAP) (n = 40) (A) and total neo-pulmonary artery index (TNPAI) (n = 38) (B). The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Overall survival (A) and survival stratified by mean pulmonary artery pressure (PAP) on the flow study (B). The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Histogram demonstrating distribution of mean pulmonary artery pressure (PAP) on the flow study and death at any point during the study. VSD, Ventricular septal defect. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

6 Figure 5 Correlation between the latest right ventricular systolic pressure/left ventricular systolic pressure (RVSP/LVSP) ratio and mean pulmonary artery pressure (PAP) on the flow study (A) or baseline total neo-pulmonary artery index (TNPAI) (B) (n = 17). The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

7 A high mean PAP (≥25 mm Hg) on a flow study is associated with poor medium-term survival.
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

8 The Journal of Thoracic and Cardiovascular Surgery 2016 152, 1494-1503
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions


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