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Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep

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Presentation on theme: "Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep"— Presentation transcript:

1 Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep
Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep. First asymmetric total synthesis of aspinolide A. Tetrahedron Letters (2009), 50(50),

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11 PMB = p-methoxybenzyl =

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23 DDQ = Dichlorodicyanoquinone

24 Removal of p-methoxybenzyl protecting group

25 Removal of p-methoxybenzyl protecting group

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27 IBX = 2-iodoxybenzoic acid =

28 IBX Mechanism IBX is less soluble than the Dess-Martin Periodinane

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30 EDCI = Ethyl(dimethylaminopropyl)carbodiimide

31 Carbodiimide Coupling Mechanism

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