1. Identification of one type of RGCs with large somas.
Identification of one type of RGCs with large somas. A, GFP-positive cells with large somas expressing Thy-1-CreERT2 transgene were coimmunolabeled with RGC markers: Brn-3a and Brn-3b (arrows). B, Small-soma, but not large-soma, GFP-positive cells were coimmunolabeled with amacrine cell markers: BETA3 and ChAT (arrowheads). C, GFP-positive cells with large somas were coimmunolabeled with RGC subtype markers: SMI-32 (arrows), but not with CART. D, Percentages of large-soma RGCs expressing Thy-1-CreERT2 transgene coimmunolabeled with different RGC markers. E, Confocal image of one large-soma RGC double-labeled by SMI-32 (red) and GFP (green). Orthogonal view of the same cell is shown at the bottom. Most SMI-32 and GFP cohorts in large RGCs (20 of 28) had their dendrites laminated in ON sublamina of IPL. Scale bars: 50 µm. INL, inner nuclear layer.
Liang Feng et al. eNeuro 2017;4:ENEURO
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