1. Destruction of a schistosomulum (arrows) in the thoracic part of the spinal cord of a BALB/c mouse at 21 days p.i.
Destruction of a schistosomulum (arrows) in the thoracic part of the spinal cord of a BALB/c mouse at 21 days p.i. (longitudinal sections). (A and B) Inflammatory lesion consisting of CD3+ lymphocytes (dark spots) (A) and microglia cells (brown-stained ramified cells) (B) that were detected by use of anti-mouse CD3+ and anti-mouse Iba-1 antibodies, respectively. Nuclei of other cells were stained blue by hematoxylin. (C and D) Tissue around the schistosomulum contains damaged axons. Axonal damage was accompanied by formation of spheroids (asterisks) in the site of axonal disruption and was visualized immunohistochemically by use of anti-mouse nonphosphorylated and phosphorylated neurofilament antibodies (SMI-311 and SMI-312, respectively) (C) and anti-mouse β-amyloid precursor protein antibodies (D). Bars, 100 μm (A and B) and 50 μm (C and D). (The figure was created by L. Lichtenbergová.)‏
Petr Horák et al. Clin. Microbiol. Rev. 2015; doi: /CMR