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Effects of short-term simultaneous infusion of dobutamine and terlipressin in patients with septic shock: the DOBUPRESS study†   A. Morelli, C. Ertmer,

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Presentation on theme: "Effects of short-term simultaneous infusion of dobutamine and terlipressin in patients with septic shock: the DOBUPRESS study†   A. Morelli, C. Ertmer,"— Presentation transcript:

1 Effects of short-term simultaneous infusion of dobutamine and terlipressin in patients with septic shock: the DOBUPRESS study†   A. Morelli, C. Ertmer, M. Lange, M. Dünser, S. Rehberg, H. Van Aken, P. Pietropaoli, M. Westphal  British Journal of Anaesthesia  Volume 100, Issue 4, Pages (April 2008) DOI: /bja/aen017 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 Study design. MAP, mean arterial pressure; CI, cardiac index.
British Journal of Anaesthesia  , DOI: ( /bja/aen017) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Systemic haemodynamics of study patients. Data are presented as mean values (sd). BL, baseline; HR, heart rate; CI, cardiac index; SVRI, systemic vascular resistance index; LVSWI, left-ventricular stroke work index; *P<0.05 Group 1 vs Group 2; †P<0.05 Group 1 vs Group 3; ‡P<0.05 Group 2 vs Group 3; §P<0.05 vs BL (in all groups). Baseline data were obtained at the fixed norepinephrine dose of 0.9 μg kg−1 min−1. British Journal of Anaesthesia  , DOI: ( /bja/aen017) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Systemic oxygen delivery, oxygen extraction, and mixed-venous oxygen saturation of study patients. Data are presented as mean values (sd). BL, baseline; DO2I, systemic oxygen delivery index; O2-ER, oxygen extraction rate; Svo2, mixed-venous oxygen saturation; *P<0.05 Group 1 vs Group 2; †P<0.05 Group 1 vs Group 3; ‡P<0.05 Group 2 vs Group 3; §P<0.05 vs BL (in all groups). Baseline data were obtained at the fixed norepinephrine dose of 0.9 μg kg−1 min−1. British Journal of Anaesthesia  , DOI: ( /bja/aen017) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Norepinephrine requirements. Data are presented as mean values (sd). BL, baseline; NE, norepinephrine; *P<0.05 Group 1 vs Group 2; †P<0.05 Group 1 vs Group 3. Baseline data were obtained at the fixed norepinephrine dose of 0.9 μg kg−1 min−1. British Journal of Anaesthesia  , DOI: ( /bja/aen017) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

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