Presentation is loading. Please wait.

Presentation is loading. Please wait.

Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R cells to PORCN inhibition Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R.

Published byJulia Emma Tikkanen Modified over 5 years ago

Similar presentations

Presentation on theme: "Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R cells to PORCN inhibition Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R."— Presentation transcript:

1 Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R cells to PORCN inhibition
Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R cells to PORCN inhibition qRT–PCR evaluation of PTPRK‐RSPO3 fusion transcript expression in VACO6, VACO6R, and HCT116 cells, as indicated. Data are expressed as means ± SD of three technical replicates from one representative experiment.Western blot showing AXIN1 protein expression in VACO6R, VACO6, and VACO6RAXIN1FL cells, as indicated.Flow cytometry analysis of the GFP signal in VACO6, VACO6R, and VACO6RAXIN1FL cells, all transduced with the 7xTcf‐eGFP WNT reporter.ATP‐based assay measuring viability, after 6 days of LGK974 treatment, of parental VACO6, VACO6R, and VACO6RAXIN1FL cells, as indicated. Data are expressed as average ± SD of six technical replicates. Source data are available online for this figure. Gabriele Picco et al. EMBO Mol Med. 2017;emmm © as stated in the article, figure or figure legend

Download ppt "Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R cells to PORCN inhibition Re‐expression of the AXIN1 coding sequence re‐sensitizes VACO6R."

Similar presentations

Effects of inhibiting inflammatory cell recruitment on fracture healing Treatment with CCR2 antagonist, INCB3344, led to impaired fracture healing compared.

Effects of inhibiting inflammatory cell recruitment on fracture healing Treatment with CCR2 antagonist, INCB3344, led to impaired fracture healing compared.
Impact of triple combination of gemcitabine‐based chemoirradiation with anti‐PD‐L1 in the KPC tumor allograft Impact of triple combination of gemcitabine‐based.

Impact of triple combination of gemcitabine‐based chemoirradiation with anti‐PD‐L1 in the KPC tumor allograft Impact of triple combination of gemcitabine‐based.
E2F7/8 and HIF1 are required for hypoxic VEGFA expression.

E2F7/8 and HIF1 are required for hypoxic VEGFA expression.
Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3 cells. Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3.

Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3 cells. Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3.
Loss of Hdac3 impairs Ar signaling in mouse prostate tissues and has no effect on apoptosis Loss of Hdac3 impairs Ar signaling in mouse prostate tissues.

Loss of Hdac3 impairs Ar signaling in mouse prostate tissues and has no effect on apoptosis Loss of Hdac3 impairs Ar signaling in mouse prostate tissues.
Network protein vulnerability in EGFR TKI‐resistant cells and specific for EGFR‐mutated cells. Network protein vulnerability in EGFR TKI‐resistant cells.

Network protein vulnerability in EGFR TKI‐resistant cells and specific for EGFR‐mutated cells. Network protein vulnerability in EGFR TKI‐resistant cells.
BRD4 expression levels are associated with sensitivity to BET inhibition in NRAS‐mutant melanoma BRD4 expression levels are associated with sensitivity.

BRD4 expression levels are associated with sensitivity to BET inhibition in NRAS‐mutant melanoma BRD4 expression levels are associated with sensitivity.
An siRNA screen identifies LIMT as an ERK‐dependent negative regulator of mammary cell migration An siRNA screen identifies LIMT as an ERK‐dependent negative.

An siRNA screen identifies LIMT as an ERK‐dependent negative regulator of mammary cell migration An siRNA screen identifies LIMT as an ERK‐dependent negative.
Expression analyses of KLK7 mRNA in the brains of AD patients

Expression analyses of KLK7 mRNA in the brains of AD patients
Induction of apoptosis by CDIP expression.

Induction of apoptosis by CDIP expression.
HDAC3 regulates AKT phosphorylation

HDAC3 regulates AKT phosphorylation
[68Ga]Pentixafor PET imaging of MM xenografts Real‐time PCR analysis of cxcr4 transcript expression levels in HeLa (negative control) and in MM cell lines.

[68Ga]Pentixafor PET imaging of MM xenografts Real‐time PCR analysis of cxcr4 transcript expression levels in HeLa (negative control) and in MM cell lines.
Expression levels of the transgenic DIA1(R1204X) mutant in the inner ear of TG mice Expression levels of the transgenic DIA1(R1204X) mutant in the inner.

Expression levels of the transgenic DIA1(R1204X) mutant in the inner ear of TG mice Expression levels of the transgenic DIA1(R1204X) mutant in the inner.
AAV8‐hAAT‐FGF21 treatment improves liver fibrosis

AAV8‐hAAT‐FGF21 treatment improves liver fibrosis
CAR T cell dose and percentages of CAR‐positive cells within CAR T cell products CAR T cell dose and percentages of CAR‐positive cells within CAR T cell.

CAR T cell dose and percentages of CAR‐positive cells within CAR T cell products CAR T cell dose and percentages of CAR‐positive cells within CAR T cell.
Luminex phosphorylation measurements are reproducible and have broad dynamic range Individual difference in insulin‐induced phosphorylation of ERK measured.

Luminex phosphorylation measurements are reproducible and have broad dynamic range Individual difference in insulin‐induced phosphorylation of ERK measured.
Phenogenetic networks of genes linked to Alzheimer's and Parkinson's disease reveal concordant phenotypes Phenogenetic networks of genes linked to Alzheimer's.

Phenogenetic networks of genes linked to Alzheimer's and Parkinson's disease reveal concordant phenotypes Phenogenetic networks of genes linked to Alzheimer's.
Reactive oxygen species inhibit miR‐199a and miR‐125b expression levels in vitro and in vivo. Reactive oxygen species inhibit miR‐199a and miR‐125b expression.

Reactive oxygen species inhibit miR‐199a and miR‐125b expression levels in vitro and in vivo. Reactive oxygen species inhibit miR‐199a and miR‐125b expression.
Functional miR‐33 responsive elements in the 3′UTR of ATP8B1 and ABCB11.A,B.Conserved sequences in the 3′UTR of ATP8B1 and ABCB11 are partially complementary.

Functional miR‐33 responsive elements in the 3′UTR of ATP8B1 and ABCB11.A,B.Conserved sequences in the 3′UTR of ATP8B1 and ABCB11 are partially complementary.
Clinical testing of calcineurin inhibitors cyclosporine A and tacrolimus in autoimmune disorders Clinical testing of calcineurin inhibitors cyclosporine.

Clinical testing of calcineurin inhibitors cyclosporine A and tacrolimus in autoimmune disorders Clinical testing of calcineurin inhibitors cyclosporine.

Similar presentations

Ads by Google