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Dilja D. Krueger, Nils Brose  Neuron 

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Presentation on theme: "Dilja D. Krueger, Nils Brose  Neuron "— Presentation transcript:

1 Evidence for a Common Endocannabinoid-Related Pathomechanism in Autism Spectrum Disorders 
Dilja D. Krueger, Nils Brose  Neuron  Volume 78, Issue 3, Pages (May 2013) DOI: /j.neuron Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Potential Role of Nlgn3 at Perisomatic Inhibitory Synapses on CA1 Pyramidal Neurons PV and CCK basket cells form perisomatic inhibitory synapses onto pyramidal neurons. Boxed inserts summarize the data reported by Földy et al. (2013). Expanded views show a model of how Nlgn3 may affect PV basket cell synapses (upper left) and CCK basket cell synapses (lower right) based on these findings. It should be noted that the presence of Nlgn3 at these synapses has not been investigated and is inferred from the data. Abbreviations: Nlgn3, Neuroligin-3; PV, parvalbumin; CCK, cholecystokinin; SV, synaptic vesicle; MOR, μ-opioid receptor; M2, M2 muscarinic acetylcholine receptor; CB1R, cannabinoid receptor type 1. Neuron  , DOI: ( /j.neuron ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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