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Sperm fluorescence in situ hybridization analysis reveals normal sperm cells for 14;14 homologous male Robertsonian translocation carrier  Cigdem Cinar,

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Presentation on theme: "Sperm fluorescence in situ hybridization analysis reveals normal sperm cells for 14;14 homologous male Robertsonian translocation carrier  Cigdem Cinar,"— Presentation transcript:

1 Sperm fluorescence in situ hybridization analysis reveals normal sperm cells for 14;14 homologous male Robertsonian translocation carrier  Cigdem Cinar, M.Sc., Cagri Beyazyurek, M.Sc., Cumhur Gokhan Ekmekci, M.D., Ph.D., Cilem Aslan, B.Sc., Semra Kahraman, M.D., Ph.D.  Fertility and Sterility  Volume 95, Issue 1, Pages 289.e5-289.e9 (January 2011) DOI: /j.fertnstert Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Karyotype of the patient: 45,XY,der(14;14)(q10;q10).
Fertility and Sterility  , 289.e5-289.e9DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 (A) Normal sperm cells after hybridization with telomeric (Tel) 14q Spectrum Orange (SO) probe. (B) Normal and abnormal sperm cells after hybridization with Tel 14q SO probe, with one signal and two signals for chromosome 14, respectively. (C) Individual normal sperm cell after hybridization with LSI 22 Spectrum Green (SG) (control)/ Tel 14q SO probe. (D) Image of individual normal sperm hybridized with LSI IGH/MAF t(14;16)(q32;q23) dual-color, dual-fusion translocation probe set: LSI 14 (SG)/LSI 16 (control) (SO). Fertility and Sterility  , 289.e5-289.e9DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Trophectoderm cells diagnosed as (A) normal and (B) monosomy 14 after hybridization with LSI IGH/MAF t(14;16) (q32;q23) dual-color, dual-fusion translocation probe set: LSI 14 (Spectrum Green [SG])/ LSI 16 (control) (Spectrum Orange [SO]). Fertility and Sterility  , 289.e5-289.e9DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions


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