1. Crossover Therapies
The Research Cycle

2. Ivermectin Heartgard + used to prevent heartworms in dogs
Merck & Co 1981 introduced as Ivomec to treat lung worms and other nematode parasites of cattle

3. Onchocerciasis (River blindness)
Found in Africa and South America
Threatens more than 100 million people with blindness
Transmitted by African black fly
Nematode=Onchocerca volvulus
worms burrow under skin and can live years and grow up to 2 feet

4. Onchocerciasis (River blindness)
when reproducing the worms release millions of microfilariae into the blood and some migrate and invade the eye

5. Onchocerciasis (River blindness)
Mectizan (Ivermectin)
kills the microfilariae
Ivermectin is the first pharmaceutical created for dogs that has been adapted for humans

6. Mectizan (Ivermectin)
Also used to treat scabies in humans

7. CDC Info