1. Amines and Amides
Section 1.7

2. Amines 1° Amine 2° Amine 3° Amine
Amine – an organic compound, related to ammonia, that contains a nitrogen atom bonded to one or more alkyl groups on each molecule.
1° Amine 2° Amine 3° Amine
Amines generally have strong, often unpleasant odours, sometimes described as fishy.

3. Naming Amines methanamine Primary Amines Secondary and Tertiary Amines
Add “amine” to the name of the chain it is attached to.
Secondary and Tertiary Amines
Begin the name based on the longest chain and add the word “amine” to the end of it and use a number to indicate where the N is located.
We use the locator, N, to indicate the attachment of additional chains to the nitrogen atom instead of a number.
methanamine
N-methylpentan-2-amine
N-ethyl-N-methylbutan-1-amine

4. Practice Name the following molecules:
Draw the structural formula for:
a) 2-methylpropan-1-amine
(b)
Propan-1-amine
N-ethyl-N-propylbutan-1-amine

5. Properties of Amines Small amines are soluble in water
N-C bond and N-H bond are polar
The primary amine can form two hydrogen bonds and hence has the highest boiling point. The tertiary cannot form hydrogen bonds and therefore has the lowest boiling point.

6. Amides
Amide – an organic compound that contains a carbonyl group bonded to a nitrogen atom.

7. Naming Amides The name of an amide has three parts
Amides are formed from the reaction of carboxylic acid and ammonia, primary amines and secondary amines.
The name of an amide has three parts
The first part from the amine
The second part from the acid
The ending which is always “amide”

8. Practice Name the following: Draw the following: a) N-ethylpropanamide
N-methylbutanamide
N,N-diethylethanamide
N-propylbutanamide

9. Properties of Amides
Smaller amides are somewhat soluble in water due to the N-H bonds which undergo hydrogen bonding.
As the length increases, solubility decreases.
Primary Amides have higher melting points and boiling points than similar amides due to more hydrogen bonding between primary amide molecules

10. Practice Naming N,N-diethyl butan-1-amine octan-3-amine
N-ethyl butan-2-amine

11. Practice Drawing a) 2-methylpropan-1-amine
b) primary amine with a 2-carbon alkyl group

12. Practice Naming
butanamide
N-propyl ethanamide
N,N-dimethyl butanamide

13. Practice Drawing
a) N,N-diethylethanamide
b) N-methylbutanamide

14. Summary of all the Naming