1. MECHANICAL PROPERTIES OF BIOLOGICAL TISSUEAND TISSUE MECHANICS
ROLL NO: 12BME 16 IQRA MEMON
ROLL NO: 12BME 27 SASUEE RAJPER

2. Tissues
Definition: a group of closely associated cells that perform related functions and are similar in structure
Between cells: nonliving extracellular material
Four basic types of tissue…function
Epithelium…covering
Connective tissue…support
Muscle tissue…movement
Nervous tissue…control

3. Tissue
Epithelial
Connective
Bone
Blood
Cartilage
Muscle Tissue
Skeletal
Cardiac
Smooth
Nervous
Neurons
Supporting cells

5. WHY STUDY SOFT TISSUE MECHANICS?
MANY BIOLOGICAL TISSUES HAVE EVOLVED TO PERFORM SPECIFIC MECHANICAL FUNCTIONS.
SOMETIMES, THESE TISSUES FAIL (PHYSICALLY AND/OR FUNCTIONALLY).

6. WHY IS IT IMPORTANT TO UNDERSTAND THE MECHANICAL FUNCTION OF TISSUES?
Obviously, prior to implantation, a replacement must be able to meet the structural requirements necessary to perform its mechanical function.
Make sure bioartificial ligament is strong enough to support loads.

7. THE MECHANICAL PROPERTIES OF BIOLOGICAL TISSUES
Stiffness
Strength
Elasticity
Ductility
Brittleness
Malleability
Toughness
Resilience
Hardness

8. Ductility – characteristic of a material that undergoes considerable plastic deformation under tensile load before rupture.
Brittleness – absence of any plastic deformation prior to failure
Fails suddenly without warning
Malleability - characteristic of a material that undergoes considerable plastic deformation under compressive load before rupture

9. Resilience – measure of energy absorbed by a material and returned when load is removed; materials that quickly return to their original shape are called resilient
Hardness -Resistance of a material to scratching, wear, or penetration

10. APPLICATION Tissue Mechanics Lab
Tissue Mechanics Lab (TML) is working to improve the treatment of cardiovascular disease by applying a unique combination of state-of-the-art computational simulations with rigorous experimental evaluation.  In the TML, techniques such as planar biaxial testing, tissue fatigue testing, vessel inflation testing, steady and pulsatile cardiac flow testing, and examination of tissue microstructure are used to quantify the mechanical properties of living tissue. This information is then implemented into dynamic solid and fluid simulations. These simulations are being used to better understand how the cardiovascular system works, and how the body interacts with implantable devices.