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Accuracy of Fluorodeoxyglucose-Positron Emission Tomography Within the Clinical Practice of the American College of Surgeons Oncology Group Z4031 Trial.

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Presentation on theme: "Accuracy of Fluorodeoxyglucose-Positron Emission Tomography Within the Clinical Practice of the American College of Surgeons Oncology Group Z4031 Trial."— Presentation transcript:

1 Accuracy of Fluorodeoxyglucose-Positron Emission Tomography Within the Clinical Practice of the American College of Surgeons Oncology Group Z4031 Trial to Diagnose Clinical Stage I Non-Small Cell Lung Cancer  Eric L. Grogan, MD, MPH, Stephen A. Deppen, MS, PhD, Karla V. Ballman, MD, Gabriela M. Andrade, MD, Francys C. Verdial, MD, Melinda C. Aldrich, MPH, PhD, Chiu L. Chen, PhD, Paul A. Decker, MS, David H. Harpole, MD, Robert J. Cerfolio, MD, Robert J. Keenan, MD, David R. Jones, MD, Thomas A. D’Amico, MD, Joseph B. Shrager, MD, Bryan F. Meyers, MD, Joe B. Putnam, MD  The Annals of Thoracic Surgery  Volume 97, Issue 4, Pages (April 2014) DOI: /j.athoracsur Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Enrolling site location, with size of circle corresponding to participation volume (small circle, 1 patient; medium circles, 10 patients; large circles, 100 patients) comprising 51 sites in 39 cities. Individual dots are participants by zip code at time of enrollment, with dots are overlapping for those with identical zip codes. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Accuracy of fluorodeoxyglucose-positron emission tomography (FDG-PET) improved with lesion size from 67% in lesions that were sized 1 to 2 cm (sensitivity, 76%; specificity, 35%) to 84% in lesions that were sized 3 to 5 cm (sensitivity, 90%; and, specificity 18%; p<0.001 by analysis of variance test). Accuracy of FDG-PET to diagnose lung cancer by lesion size in millimeters: Accuracy = (true positives + true negatives)/total population. The range bars show the 95% confidence interval. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions


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