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Ee-chun Cheng, Haifan Lin  Developmental Cell 

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1 Repressing the Repressor: A lincRNA as a MicroRNA Sponge in Embryonic Stem Cell Self-Renewal 
Ee-chun Cheng, Haifan Lin  Developmental Cell  Volume 25, Issue 1, Pages 1-2 (April 2013) DOI: /j.devcel Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 A Competition for miR-145 between linc-RoR and mRNAs Encoding the Core TFs The presence of linc-RoR in hESCs traps miR-145, preventing it from repressing the translation of the core pluripotency factors and ensuring the stem cell fate. The disappearance of linc-RoR in differentiating hESCs releases miR-145, allowing it to repress the translation of core pluripotency factors. Developmental Cell  , 1-2DOI: ( /j.devcel ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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