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An Accelerated Infliximab Induction Regimen Reduces the Need for Early Colectomy in Patients With Acute Severe Ulcerative Colitis  David J. Gibson, Zaid.

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Presentation on theme: "An Accelerated Infliximab Induction Regimen Reduces the Need for Early Colectomy in Patients With Acute Severe Ulcerative Colitis  David J. Gibson, Zaid."— Presentation transcript:

1 An Accelerated Infliximab Induction Regimen Reduces the Need for Early Colectomy in Patients With Acute Severe Ulcerative Colitis  David J. Gibson, Zaid S. Heetun, Ciaran E. Redmond, Kavin S. Nanda, Denise Keegan, Kathryn Byrne, Hugh E. Mulcahy, Garret Cullen, Glen A. Doherty  Clinical Gastroenterology and Hepatology  Volume 13, Issue 2, Pages e1 (February 2015) DOI: /j.cgh Copyright © 2015 AGA Institute Terms and Conditions

2 Figure 1 Median daily CRP after induction comparing SD induction and AD induction, with area under the curve (AUC) values for each induction regimen. Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

3 Figure 2 Kaplan–Meier curve showing estimates of proportion of patients requiring colectomy with time, comparing patients who had SD IFX induction (dashed line) and those who had AD IFX induction (bold line). Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

4 Figure 3 Kaplan–Meier curve showing estimates of proportion of patients requiring colectomy with time, comparing patients who completed induction and had SD IFX induction (dashed line) and those who had AD IFX induction (bold line). FU, follow-up. Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions

5 Supplementary Figure 1 Kaplan–Meier curve showing estimates of proportion of patients requiring colectomy with time, comparing patients who completed induction and achieved normal CRP during induction (dashed line) and those who had persistently elevated CRP during induction (bold line). FU, follow-up. Clinical Gastroenterology and Hepatology  , e1DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions


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