Presentation is loading. Please wait.

Presentation is loading. Please wait.

Sensory-Motor Circuits: Hox Genes Get in Touch

Published byVernon Roger Robertson Modified over 5 years ago

Similar presentations

Presentation on theme: "Sensory-Motor Circuits: Hox Genes Get in Touch"— Presentation transcript:

1 Sensory-Motor Circuits: Hox Genes Get in Touch
Polyxeni Philippidou, Jeremy S. Dasen  Neuron  Volume 88, Issue 3, Pages (November 2015) DOI: /j.neuron Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Hox Genes Govern the Assembly of a Touch-Reflex Circuit in C. elegans (A) Summary of defects in TRN development in indicated mutant and transgenic lines. Deletion of the posterior Hox gene egl-5 results in a PLM to ALM transformation, including cell body displacement (black arrowhead), while egl-5 overexpression imposes a PLM fate on ALM neurons (white arrowhead). Rfip-1 mutants show shortening of the posterior PLM neurite, similar to egl-5 deletion, but cell body position is unaffected. A partial list of differentially expressed genes in ALM and PLM is shown on the right. (B) Genetic interactions between Hox, Hox cofactors, and target effectors during PLM differentiation. (C) Diagram of circuits controlling forward and reverse movement in response to posterior and anterior touch respectively. PLM to PVC functional connectivity requires egl-5. SN, sensory neuron; IN, interneuron; MN, motor neuron. Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

Download ppt "Sensory-Motor Circuits: Hox Genes Get in Touch"

Similar presentations

The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages 733-745 (September 2009) DOI:

The Neurobiology of Decision: Consensus and Controversy Joseph W. Kable, Paul W. Glimcher Neuron Volume 63, Issue 6, Pages (September 2009) DOI:
Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies B.J. Casey, Charles E. Glatt, Francis S. Lee Neuron Volume.

Treating the Developing versus Developed Brain: Translating Preclinical Mouse and Human Studies B.J. Casey, Charles E. Glatt, Francis S. Lee Neuron Volume.
Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics Timothy P. Lillicrap, Stephen H. Scott.

Preference Distributions of Primary Motor Cortex Neurons Reflect Control Solutions Optimized for Limb Biomechanics Timothy P. Lillicrap, Stephen H. Scott.
The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages 844-866 (November 2013) DOI: 10.1016/j.neuron.2013.10.008 Copyright.

The Pathobiology of Vascular Dementia Costantino Iadecola Neuron Volume 80, Issue 4, Pages (November 2013) DOI: /j.neuron Copyright.
Intensity-Dependent Adaptation of Cortical and Thalamic Neurons Is Controlled by Brainstem Circuits of the Sensory Pathway Elad Ganmor, Yonatan Katz, Ilan.

Intensity-Dependent Adaptation of Cortical and Thalamic Neurons Is Controlled by Brainstem Circuits of the Sensory Pathway Elad Ganmor, Yonatan Katz, Ilan.
Decision Making as a Window on Cognition Michael N. Shadlen, Roozbeh Kiani Neuron Volume 80, Issue 3, Pages 791-806 (October 2013) DOI: 10.1016/j.neuron.2013.10.047.

Decision Making as a Window on Cognition Michael N. Shadlen, Roozbeh Kiani Neuron Volume 80, Issue 3, Pages (October 2013) DOI: /j.neuron
Canonical Microcircuits for Predictive Coding Andre M. Bastos, W. Martin Usrey, Rick A. Adams, George R. Mangun, Pascal Fries, Karl J. Friston Neuron Volume.

Canonical Microcircuits for Predictive Coding Andre M. Bastos, W. Martin Usrey, Rick A. Adams, George R. Mangun, Pascal Fries, Karl J. Friston Neuron Volume.
Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages 951-962 (June 2006) DOI: 10.1016/j.neuron.2006.04.035.

Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages (June 2006) DOI: /j.neuron
Encoding of Both Analog- and Digital-like Behavioral Outputs by One C. elegans Interneuron Zhaoyu Li, Jie Liu, Maohua Zheng, X.Z. Shawn Xu Cell Volume.

Encoding of Both Analog- and Digital-like Behavioral Outputs by One C. elegans Interneuron Zhaoyu Li, Jie Liu, Maohua Zheng, X.Z. Shawn Xu Cell Volume.
Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages 1262-1272 (September 2014)

Neuronal Cell Types and Connectivity: Lessons from the Retina H. Sebastian Seung, Uygar Sümbül Neuron Volume 83, Issue 6, Pages (September 2014)
Normal Movement Selectivity in Autism Ilan Dinstein, Cibu Thomas, Kate Humphreys, Nancy Minshew, Marlene Behrmann, David J. Heeger Neuron Volume 66, Issue.

Normal Movement Selectivity in Autism Ilan Dinstein, Cibu Thomas, Kate Humphreys, Nancy Minshew, Marlene Behrmann, David J. Heeger Neuron Volume 66, Issue.
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka.

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease Nobutaka Hirokawa, Shinsuke Niwa, Yosuke Tanaka.
Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.

Synapse-Specific Adaptations to Inactivity in Hippocampal Circuits Achieve Homeostatic Gain Control while Dampening Network Reverberation Jimok Kim, Richard.
Pyramidal Neurons Grow Up and Change Their Mind Gord Fishell, Carina Hanashima Neuron Volume 57, Issue 3, Pages 333-338 (February 2008) DOI: 10.1016/j.neuron.2008.01.018.

Pyramidal Neurons Grow Up and Change Their Mind Gord Fishell, Carina Hanashima Neuron Volume 57, Issue 3, Pages (February 2008) DOI: /j.neuron
Hippocampal Activity Patterns Carry Information about Objects in Temporal Context Liang-Tien Hsieh, Matthias J. Gruber, Lucas J. Jenkins, Charan Ranganath.

Hippocampal Activity Patterns Carry Information about Objects in Temporal Context Liang-Tien Hsieh, Matthias J. Gruber, Lucas J. Jenkins, Charan Ranganath.
Dissociable Medial Prefrontal Contributions to Judgments of Similar and Dissimilar Others Jason P. Mitchell, C. Neil Macrae, Mahzarin R. Banaji Neuron.

Dissociable Medial Prefrontal Contributions to Judgments of Similar and Dissimilar Others Jason P. Mitchell, C. Neil Macrae, Mahzarin R. Banaji Neuron.
Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages 26-39 (July 2012) DOI: 10.1016/j.neuron.2012.06.018.

Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron
Adaptation to Natural Binocular Disparities in Primate V1 Explained by a Generalized Energy Model Ralf M. Haefner, Bruce G. Cumming Neuron Volume 57, Issue.

Adaptation to Natural Binocular Disparities in Primate V1 Explained by a Generalized Energy Model Ralf M. Haefner, Bruce G. Cumming Neuron Volume 57, Issue.
Reading the Book of Memory: Sparse Sampling versus Dense Mapping of Connectomes H. Sebastian Seung Neuron Volume 62, Issue 1, Pages 17-29 (April 2009)

Reading the Book of Memory: Sparse Sampling versus Dense Mapping of Connectomes H. Sebastian Seung Neuron Volume 62, Issue 1, Pages (April 2009)
Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages 305-320 (March 2005) DOI: 10.1016/j.devcel.2005.02.007.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Similar presentations

Ads by Google