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Prosthesis-Patient Mismatch After Aortic Valve Replacement: Impact of Age and Body Size on Late Survival  Marc R. Moon, MD, Michael K. Pasque, MD, Nabil.

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Presentation on theme: "Prosthesis-Patient Mismatch After Aortic Valve Replacement: Impact of Age and Body Size on Late Survival  Marc R. Moon, MD, Michael K. Pasque, MD, Nabil."— Presentation transcript:

1 Prosthesis-Patient Mismatch After Aortic Valve Replacement: Impact of Age and Body Size on Late Survival  Marc R. Moon, MD, Michael K. Pasque, MD, Nabil A. Munfakh, MD, Spencer J. Melby, MD, Jennifer S. Lawton, MD, Nader Moazami, MD, John E. Codd, MD, Traves D. Crabtree, MD, Hendrick B. Barner, MD, Ralph J. Damiano, MD  The Annals of Thoracic Surgery  Volume 81, Issue 2, Pages (February 2006) DOI: /j.athoracsur Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Numbers of bioprosthetic (solid circles) and mechanical (open circles) aortic valves implanted from 1986 to 2004 (total 2004 projected). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Late survival estimates after aortic valve replacement for all patients (including operative deaths [solid circles]) and for operative survivors (open circles). The numbers of patients at risk at 1, 5, and 8 years are indicated. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Impact of prosthesis-patient mismatch (PPM) on late survival after aortic valve replacement in patients less than 60 years of age (p < 0.001). The numbers of patients at risk at 1, 5, and 8 years are indicated. (Solid circles = PPM 0.75 cm2/m2 or greater; open circles = PPM less than 0.75 cm2/m2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Impact of prosthesis-patient mismatch (PPM) on late survival after aortic valve replacement in patients 60 years of age or more (p = 0.95). The numbers of patients at risk at 1, 5, and 8 years are indicated. (Solid circles = PPM 0.75 cm2/m2 or greater; open circles = PPM less than 0.75 cm2/m2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Impact of prosthesis-patient mismatch (PPM) on late survival after aortic valve replacement in large patients (body surface area greater than 2.1 m2; p > 0.02). The numbers of patients at risk at 1, 5, and 8 years are indicated. (Solid circles = PPM 0.75 cm2/m2 or greater; open circles = PPM less than 0.75 cm2/m2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Impact of prosthesis-patient mismatch (PPM) on late survival after aortic valve replacement in average-size patients (body surface area 1.7 m2 to 2.1 m2; p < 0.001). The numbers of patients at risk at 1, 5, and 8 years are indicated. (Solid circles = PPM 0.75 cm2/m2 or greater; open circles = PPM less than 0.75 cm2/m2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

8 Fig 7 Impact of prosthesis-patient mismatch (PPM) on late survival after aortic valve replacement in small patients (body surface area less than 1.7 m2; p = 0.66). For consistency, the numbers of patients at risk at 1, 5, and 8 years are indicated below the lines for PPM and above the lines for no PPM. (Solid circles = PPM 0.75 cm2/m2 or greater; open circles = PPM less than 0.75 cm2/m2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions


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