1. The major issue that the authors set out to address is
How Bid acts to induce apoptosis
How Bcl-2 acts to prevent apoptosis
What is cytochrome c releasing factor?
How does the death receptor relay the apoptosis signal to mitochondria?
All of the above

2. The cytochrome c releasing activity of Bid comes from
its amino terminal part after caspase-8 cleavage
the full-length protein
the carboxyl terminal part after caspase-8 cleavage
the BH3 motif
None of the above

3. The Bid(G94E) mutant is compromised in
binding mitochondria
being cleaved by caspase-8
inducing cytochrome c release
binding to Bcl-2
All of the above

4. The Bid(D59A) mutant is compromised in
binding mitochondria
being cleaved by caspase-8
inducing cytochrome c release
D. All of the above

5. What is the most interesting question that remains to be addressed after this study?
How does truncated Bid act to induce cytochrome c release?
How does Bcl-2 acts to prevent apoptosis?
Are there other cytochrome c releasing factors?
How does the death receptor relay the apoptosis signal to mitochondria?
How does truncated Bid bind to mitochondria?