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Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate  Matthew Remedios,

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Presentation on theme: "Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate  Matthew Remedios,"— Presentation transcript:

1 Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate  Matthew Remedios, MBBS, Catherine Campbell, MBBS, Dianne M. Jones, B App Sc, Paul Kerlin, MD  Gastrointestinal Endoscopy  Volume 63, Issue 1, Pages 3-12 (January 2006) DOI: /j.gie Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

2 Figure 1 A, Linear furrows in esophageal lumen. B, Mucosal rings. C, Multiple white papules/plaques in esophagus. D, Histologic appearance of esophageal biopsy specimens, demonstrating markedly increased intraepithelial eosinophils. (H&E, orig. mag. ×100). Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

3 Figure 1 A, Linear furrows in esophageal lumen. B, Mucosal rings. C, Multiple white papules/plaques in esophagus. D, Histologic appearance of esophageal biopsy specimens, demonstrating markedly increased intraepithelial eosinophils. (H&E, orig. mag. ×100). Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

4 Figure 1 A, Linear furrows in esophageal lumen. B, Mucosal rings. C, Multiple white papules/plaques in esophagus. D, Histologic appearance of esophageal biopsy specimens, demonstrating markedly increased intraepithelial eosinophils. (H&E, orig. mag. ×100). Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

5 Figure 1 A, Linear furrows in esophageal lumen. B, Mucosal rings. C, Multiple white papules/plaques in esophagus. D, Histologic appearance of esophageal biopsy specimens, demonstrating markedly increased intraepithelial eosinophils. (H&E, orig. mag. ×100). Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

6 Figure 2 Symptom score before and after treatment with swallowed fluticasone propionate. Cumulative symptom score based on presence and frequency of dysphagia, chest pain, heartburn, regurgitation, vomiting, and abdominal pain (each scored 0 to 3). Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions

7 Figure 3 Mean eosinophils/HPF in proximal and distal esophageal biopsy specimens before and after treatment with swallowed fluticasone propionate. Gastrointestinal Endoscopy  , 3-12DOI: ( /j.gie ) Copyright © 2006 American Society for Gastrointestinal Endoscopy Terms and Conditions


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