1. The Gene for May-Hegglin Anomaly Localizes to a <1-Mb Region on Chromosome 22q12.3-13.1 
John A. Martignetti, Karen E. Heath, Juliette Harris, Nicola Bizzaro, Anna Savoia, Carlo L. Balduini, Robert J. Desnick 
The American Journal of Human Genetics 
Volume 66, Issue 4, Pages (April 2000)
DOI: /302873
Copyright © 2000 The American Society of Human Genetics Terms and Conditions

2. Figure 1
Pedigree of the Italian kindred with MHA. This family was previously described elsewhere (Bizzaro 1997), and we have herein updated its members' disease status. Family members in the present study are numbered. Blackened symbols denote affected individuals; unblackened symbols denote unaffected individuals. Affected individual V.3 (gray-shaded circle) also has von Willebrand disease.
The American Journal of Human Genetics  , DOI: ( /302873)
Copyright © 2000 The American Society of Human Genetics Terms and Conditions

3. Figure 2
Haplotypes of the kindred with MHA. Twelve markers (D22S345, D22S277, D22S1142, D22S683, D22S283, D22S1177, IL2RB, D22S445, D22S272, D22S284, D22S423, and D22S444) from within and flanking the linkage region are shown. Family numbers and individual numbers are the same as those infigure 1. Affected individuals are underlined with a blackened bar; unaffected individuals are underlined with an unblackened bar. Spouses are shown to determine phase.
The American Journal of Human Genetics  , DOI: ( /302873)
Copyright © 2000 The American Society of Human Genetics Terms and Conditions

4. Figure 3
Chromosome 22 ideogram. The markers used in this study are shown with their relative locations and genetic distances, as previously defined (Broman et al. 1998), and with the actual physical distances based on chromosome 22 sequence data (Dunham et al. 1999).
The American Journal of Human Genetics  , DOI: ( /302873)
Copyright © 2000 The American Society of Human Genetics Terms and Conditions