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A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma

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Presentation on theme: "A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma"— Presentation transcript:

1 A Meta-Analysis of Postoperative Radiotherapy for Thymic Carcinoma
Masatsugu Hamaji, MD, PhD, Rohan M. Shah, MS, Syed Osman Ali, MD, Aaron Bettenhausen, MD, Hyun-Sung Lee, MD, PhD, Bryan M. Burt, MD  The Annals of Thoracic Surgery  Volume 103, Issue 5, Pages (May 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Preferred Reporting Items for Systematic Reviews and Meta-Analysis flow chart for literature search and study selection. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Comparisons of (A) overall survival and (B) progression-free survival after postoperative radiotherapy (PORT) versus no PORT with meta-analysis using random effects model. The left portion of the figure shows the studies analyzed with their corresponding hazard ratio, lower and upper confidence interval (CI) limits, and p value; the right portion of the figure shows a forest plot of the data. The horizontal lines represent the values within the 95% confidence interval (CI) of the underlying effects; the vertical line indicates a hazard ratio of 1. (SEER = Surveillance, Epidemiology, and End Results.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 A funnel plot of precision by log hazard ratio for (A) overall survival and (B) progression-free survival showed that all the studies in our meta-analysis fall almost symmetrically and most are centered on the median axis, suggesting a lack of important publication bias in our meta-analysis in all the original studies. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

5 Supplemental Figure Kaplan-Meier estimates of overall survival among patients undergoing postoperative radiotherapy (PORT) and patients undergoing no PORT in the Surveillance, Epidemiology, and End Results dataset. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

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