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C.E. Nord, D.A. Gajjar, D.M. Grasela 

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Presentation on theme: "C.E. Nord, D.A. Gajjar, D.M. Grasela "— Presentation transcript:

1 Ecological impact of the des-F(6)-quinolone, BMS-284756, on the normal intestinal microflora 
C.E. Nord, D.A. Gajjar, D.M. Grasela  Clinical Microbiology and Infection  Volume 8, Issue 4, Pages (April 2002) DOI: /j x Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

2 Figure 1 Impact of BMS given as 400-mg capsules daily for 14 days on the intestinal aerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

3 Figure 2 Impact of BMS given as 400-mg capsules daily for 14 days on the intestinal anaerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

4 Figure 3 Impact of BMS given as 800-mg capsules daily for 14 days on the intestinal aerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

5 Figure 4 Impact of BMS given as 800-mg capsules daily for 14 days on the intestinal anaerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

6 Figure 5 Impact of BMS given as 1200-mg capsules daily for 14 days on the intestinal aerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

7 Figure 6 Impact of BMS given as 1200-mg capsules daily for 14 days on the intestinal anaerobic microflora in six subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

8 Figure 7 Impact of placebo capsules given daily for 14 days on the intestinal aerobic microflora in 10 subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions

9 Figure 8 Impact of placebo capsules given daily for 14 days on the intestinal anaerobic microflora in 10 subjects. Line indicates median value of the logarithmic number of micro-organisms/g feces. Clinical Microbiology and Infection 2002 8, DOI: ( /j x) Copyright © 2002 European Society of Clinical Infectious Diseases Terms and Conditions


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