Presentation is loading. Please wait.

Presentation is loading. Please wait.

Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney.

Similar presentations


Presentation on theme: "Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney."— Presentation transcript:

1 Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney Transplantation: A Population Cohort Study  Wai H. Lim, David W. Johnson, Carmel M. Hawley, Elaine Pascoe, Germaine Wong  American Journal of Kidney Diseases  Volume 71, Issue 1, Pages (January 2018) DOI: /j.ajkd Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Cumulative incidence function curves of (A) death-censored graft loss (DCGL) and (B) death with a functioning graft (DWFG) after kidney transplantation stratified by cumulative vascular disease burden, adjusted for the competing risk for DWFG and DCGL, respectively. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 Forest plots show the adjusted subdistribution hazard ratio (HR) with 95% confidence interval (95% CI) of the associations between cumulative vascular disease burden, cardiovascular disease (CVD) mortality, infection-related mortality, cancer-related mortality, and other vascular disease–related mortality. Models adjusted for donor and recipient age, waiting time, body mass index, sex, transplantation era, and race. Estimates of subdistribution HRs were derived from the competing-risk models using the Fine and Gray method. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

4 Figure 3 Cumulative incidence function curves of cardiovascular disease (CVD) mortality stratified by cumulative vascular disease burden, adjusted for the competing risk for non–CVD-related mortality. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

5 Figure 4 Forest plots show adjusted hazard ratios (HRs) or adjusted subdistribution HRs with 95% confidence intervals (CIs) of the associations between cumulative vascular disease burden, all-cause mortality, overall transplant loss, death with functioning transplant, and cardiovascular disease (CVD) mortality according to pretransplantation diabetes status. Models adjusted for donor and recipient age, waiting time, body mass index, sex, transplantation era, and race. #Estimates of subdistribution HRs were derived from competing-risk models using the Fine and Gray method. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions


Download ppt "Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney."

Similar presentations


Ads by Google