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Clinical experience with CorMatrix extracellular matrix in the surgical treatment of mitral valve disease  Marc W. Gerdisch, MD, FACS, FACC, Richard J.

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Presentation on theme: "Clinical experience with CorMatrix extracellular matrix in the surgical treatment of mitral valve disease  Marc W. Gerdisch, MD, FACS, FACC, Richard J."— Presentation transcript:

1 Clinical experience with CorMatrix extracellular matrix in the surgical treatment of mitral valve disease  Marc W. Gerdisch, MD, FACS, FACC, Richard J. Shea, MD, Michael D. Barron, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 148, Issue 4, Pages (October 2014) DOI: /j.jtcvs Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Patient 15, posterior leaflet repair. A and B, Decalcification of the mitral valve annulus and P1-P2 segments. C, Extracellular matrix bioscaffold patch augmentation. D, Completed mitral valve repair tested under pressure for valve competence. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Patient 10, decalcification and repair of annulus and P3. A, Debridement of calcified tissue. B, Extracellular matrix bioscaffold patch augmentation. C, Adjustment of neochordae. D, Completed mitral valve repair. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Patient 18, annular decalcification and leaflet repair. A, Decalcification. B, Annular reconstruction with extracellular matrix bioscaffold. C, Leaflet reattached and neochordae implanted. D, Completed mitral valve repair. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Patient 2, histopathologic results from explantation from a patient with a history of chemotherapy and radiotherapy. A, Hematoxylin-eosin stain (×100) showing regions of vascularized (right arrow) and avascular (left arrow) graft material. The arrowhead denotes the hole left by the suture. B, Immunohistochemical stain for CD31 (×400). Positive areas indicate probable endothelial cells, suggesting partial vascularization of some regions of the explanted graft (arrows). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

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