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MTX-PG concentrations and hepatotoxicity.

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Presentation on theme: "MTX-PG concentrations and hepatotoxicity."— Presentation transcript:

1 MTX-PG concentrations and hepatotoxicity.
MTX-PG concentrations and hepatotoxicity. (A) Maximum MTX-PG concentrations among groups with or without hepatotoxicity; (B) cut-off values of total MTX-PG concentration for AST/ALT ≥50 and (C) cut-off values of total MTX-PG concentration for AST/ALT ≥100. *p<0.05. ALT, alanine transaminase; AST, aspartate transaminase; AUC, area under the curve; DAS28, Disease Activity Score for 28 joints; MTX-PG, methotrexate polyglutamate. Chihiro Takahashi et al. RMD Open 2017;3:e000363 Copyright © BMJ Publishing Group & EULAR. All rights reserved.

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