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Volume 57, Issue 1, Pages (January 2000)

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Presentation on theme: "Volume 57, Issue 1, Pages (January 2000)"— Presentation transcript:

1 Volume 57, Issue 1, Pages 274-281 (January 2000)
ACE genotype and ACE inhibitors induced renoprotection in chronic proteinuric nephropathies1  Annalisa Perna, Piero Ruggenenti, Alessandra Testa, Belinda Spoto, Roberto Benini, Valerio Misefari, Giuseppe Remuzzi, Carmine Zoccali, for the Gruppo Italiano di Studi Epidemiologici in Nefrologia (GISEN)  Kidney International  Volume 57, Issue 1, Pages (January 2000) DOI: /j x Copyright © 2000 International Society of Nephrology Terms and Conditions

2 Figure 1 Rate of glomerular filtration rate (β;GFR; A) and incidence of events (B) according to different insertion/deletion (I/D) genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

3 Figure 2 β;GFR according to ramipril () or conventional () treatment and different I/D genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

4 Figure 3 Incidence of events according to ramipril () or conventional () treatment and different I/D genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

5 Figure 4 Kidney survival according to ramipril or conventional treatment in patients with DD genotype. Ramipril, • (6 events); conventional treatment, ○ (16 events). Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

6 Figure 5 Median percentage reduction in urinary protein excretion rate at three months versus baseline values according to ramipril () or conventional () treatment and different I/D genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

7 Figure 5 Median percentage reduction in urinary protein excretion rate at three months versus baseline values according to ramipril () or conventional () treatment and different I/D genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

8 Figure 5 Median percentage reduction in urinary protein excretion rate at three months versus baseline values according to ramipril () or conventional () treatment and different I/D genotypes. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions

9 Figure 6 Correlation between median three-month percentage changes in urinary protein excretion rate and β;GFR during the whole follow-up period in patients with DD genotype.N = 33; r = -0.41; P = 0.02. Kidney International  , DOI: ( /j x) Copyright © 2000 International Society of Nephrology Terms and Conditions


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