1. Do Longer Oars Row Farther?
Roger Cooke 
Molecular Cell 
Volume 10, Issue 5, Pages (November 2002)
DOI: /S (02)

2. Figure 1 Myosin Displacement
(A) Synthesis of structural and biochemical studies has led to a widely, but not universally, accepted model of how the actomyosin interaction produces force and displacement. The myosin head consists of two regions, a large globular region, the motor domain, that interacts with actin and with nucleotides, and a cylindrical region composed of 1–6 light chains wrapped around an α helix, the light chain domain. The motor domain is thought to bind to actin with the force-generating power stroke produced by a rotation of the light chain domain, which acts like a lever arm. Each light chain provides approximately 4 nm to the length of the light chain domain.
(B) The stroke lengths measured by Purcell et al. (solid squares) are compared to those produced by a series of myosin constructs studied previously (open squares) (data are averages taken from Table 2 of Tyska and Warshaw, 2002). The length of the processive steps taken by the short construct of Tanaka et al. is also shown (solid diamond).
Molecular Cell  , DOI: ( /S (02) )

3. Figure 1 Myosin Displacement
(A) Synthesis of structural and biochemical studies has led to a widely, but not universally, accepted model of how the actomyosin interaction produces force and displacement. The myosin head consists of two regions, a large globular region, the motor domain, that interacts with actin and with nucleotides, and a cylindrical region composed of 1–6 light chains wrapped around an α helix, the light chain domain. The motor domain is thought to bind to actin with the force-generating power stroke produced by a rotation of the light chain domain, which acts like a lever arm. Each light chain provides approximately 4 nm to the length of the light chain domain.
(B) The stroke lengths measured by Purcell et al. (solid squares) are compared to those produced by a series of myosin constructs studied previously (open squares) (data are averages taken from Table 2 of Tyska and Warshaw, 2002). The length of the processive steps taken by the short construct of Tanaka et al. is also shown (solid diamond).
Molecular Cell  , DOI: ( /S (02) )