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Volume 144, Issue 3, Pages (September 2013)

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Presentation on theme: "Volume 144, Issue 3, Pages (September 2013)"— Presentation transcript:

1 Volume 144, Issue 3, Pages 896-902 (September 2013)
CPAP Improves Endothelial Function in Patients With Minimally Symptomatic OSA  Malcolm Kohler, MD, Sonya Craig, Justin C.T. Pepperell, MD, Debby Nicoll, PhD, Daniel J. Bratton, MSc, Andrew J. Nunn, MSc, Paul Leeson, PhD, John R. Stradling, MD  CHEST  Volume 144, Issue 3, Pages (September 2013) DOI: /chest Copyright © 2013 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Consort diagram. FMD = flow-mediated dilatation; PWA = pulse wave analysis. CHEST  , DOI: ( /chest ) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Forest plot showing a significant treatment effect of CPAP on endothelial function, assessed by FMD of the brachial artery, compared with standard care. There was no significant treatment effect of CPAP on arterial stiffness, assessed by augmentation index, compared with standard care. See Figure 1 legend for expansion of abbreviation. CHEST  , DOI: ( /chest ) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Forest plot showing no statistically significant difference in the treatment effect on augmentation index in patients using CPAP < 4 h/night compared with those using it ≥ 4 h/night. The dashed line represents the overall treatment effect. CHEST  , DOI: ( /chest ) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

5 Figure 4 Forest plot showing a statistically significant difference in the treatment effect on FMD of the brachial artery in patients using CPAP < 4 h/night compared with those using it ≥ 4 h/night. The dashed line represents the overall treatment effect. See Figure 1 legend for expansion of abbreviation. CHEST  , DOI: ( /chest ) Copyright © 2013 The American College of Chest Physicians Terms and Conditions


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