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Volume 15, Issue 1, Pages (January 2014)

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Presentation on theme: "Volume 15, Issue 1, Pages (January 2014)"— Presentation transcript:

1 Volume 15, Issue 1, Pages 78-86 (January 2014)
Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial  Dr Hugo E R Ford, MD, Andrea Marshall, PhD, John A Bridgewater, PhD, Tobias Janowitz, PhD, Fareeda Y Coxon, MRCP, Jonathan Wadsley, FRCR, Wasat Mansoor, PhD, David Fyfe, MD, Srinivasan Madhusudan, FRCP, Prof Gary W Middleton, MD, Daniel Swinson, MD, Stephen Falk, MD, Ian Chau, MD, Prof David Cunningham, MD, Paula Kareclas, PhD, Natalie Cook, PhD, Prof Jane M Blazeby, MD, Prof Janet A Dunn, PhD  The Lancet Oncology  Volume 15, Issue 1, Pages (January 2014) DOI: /S (13) Copyright © 2014 Ford et al. Open Access article distributed under the terms of CC BY Terms and Conditions

2 Figure 1 Trial profile The Lancet Oncology  , 78-86DOI: ( /S (13) ) Copyright © 2014 Ford et al. Open Access article distributed under the terms of CC BY Terms and Conditions

3 Figure 2 Kaplan-Meier plot of overall survival
The Lancet Oncology  , 78-86DOI: ( /S (13) ) Copyright © 2014 Ford et al. Open Access article distributed under the terms of CC BY Terms and Conditions

4 Figure 3 Hazard ratio plot of the treatment effect by prognostic factors for overall survival ECOG PS=Eastern Cooperative Oncology Group performance status. The Lancet Oncology  , 78-86DOI: ( /S (13) ) Copyright © 2014 Ford et al. Open Access article distributed under the terms of CC BY Terms and Conditions

5 Figure 4 Health-related quality of life (HRQL) outcomes.
Positive values in function scale and negative values for the symptom scale denote benefit from docetaxel compared with active symptom control. The Lancet Oncology  , 78-86DOI: ( /S (13) ) Copyright © 2014 Ford et al. Open Access article distributed under the terms of CC BY Terms and Conditions


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