Presentation is loading. Please wait.

Presentation is loading. Please wait.

Apoptosis: Letting Slip The Dogs Of War

Similar presentations


Presentation on theme: "Apoptosis: Letting Slip The Dogs Of War"— Presentation transcript:

1 Apoptosis: Letting Slip The Dogs Of War
Beni B Wolf, Douglas R Green  Current Biology  Volume 12, Issue 5, Pages R177-R179 (March 2002) DOI: /S (02)

2 Fig. 1 Cell death pathways modulated by Omi. Caspase-dependent (green) and caspase-independent (blue) cell death pathways regulated by mitochondria. Smac/Diablo and Omi may function in both pathways, whereas cytochrome c appears to function primarily to activate caspases. (See text for details.) Current Biology  , R177-R179DOI: ( /S (02) )

3 Fig. 2 Omi and related IAP-binding proteins. (A) The Omi domain structure highlighting the mitochondrial translocation sequence (MTS), the trypsin-like protease domain and the PDZ domain (which may function in protein–protein interactions. AVPS is the IAP-binding motif, and SPRS the putative stress kinase phosphorylation site. (B) A comparison of IAP-binding motifs defined to date. Current Biology  , R177-R179DOI: ( /S (02) )


Download ppt "Apoptosis: Letting Slip The Dogs Of War"

Similar presentations


Ads by Google