1. Simulation of Light Ion Fragmentation Experiments Using GEANT4
Iwan Cornelius, Faiza Bourhaleb,
Roberto Cirio, Flavio Marchetto
Introduce yourself
What are you doing in Italy
Say a few brief words about simulation of light ion fragmentation experiments
Work in progress so results are tentative

2. Torino INFN Italian Heavy Ion Therapy Facility (CNAO)
Development of beam monitoring hardware
Treatment planning research
Physics of ion interaction
Radiobiology
Torino section infn actively involved with research for future HIT facility in pavia
Two branches to work
Development of beam monitoring system: pixel ionisation chamber
Research into treatment planning system for HIT
I am involved with the treatment planning aspect of research.
Treatment planning in HIT requires particular attention to the following
Unique aspect of physics of interaction is the fragmentation of carbon ions
Analytical treatment planning system similar to GSI TRIP

3. Fragmentation Models
Current TPS (ANCOD) requires fluence spectra of primary and secondaries with depth in patient f(Z,E,t)H2O
Information used with Radiobiological model to calculate equivalent dose
In past produced by GEANT3 w. FREESCO interface
Investigate models of fragmentation
Quantum Molecular Dynamics
JQMD + Interface to GEANT4
GEANT Includes binary cascade model

4. Model Verification Simulate fragmentation experiments
Schall (GSI): Fragment yields (Z>4) for varying thickness water target
Matsufuji (NIRS): fragment yields (Z>1) for varying thickness PMMA target
Gunzert-Marx (GSI): fragment spectroscopy and angular dependence (n,p,d,t,He-3,a)

5. G4 Ion Physics G4MultipleScattering G4ionIonisation
G4HadronInelasticProcess
G4TripathiCrossSection
G4IonsShenCrossSection
G4BinaryLightIonReaction

6. Schall et.al. 1996 Beam : C-12 676 AMeV
Target : H2O (variable thickness, t)
Detection system : Ionisation Chamber f(DE)
Information : N(Z,t) /No

7. Geometry Ionisation Chamber Target Beam Selection System
Position X 20 x 20 cm 34mm P-10
Position Y 20 x 20 cm 34mm P-10
IC 20 x 20 cm 43mm P-10
Target water 20 x 20 cm t

8. Results

9. Gunzert-Marx et.al. 2003 Beam : C-12 200 AMeV
Target : H2O (T>>R)
Detection system : Detector Telescope f(DE, E), TOF system
Information : N(q,E,X)

10. Geometry
Target
Telescope
Start / IC q

11. To do
Simulate other data from Schall 1996 experiments with heavier ions O, N
Simulate Gunzert-Marx experiment
Simulate experiment of Matsufuji et.al.
Quantitative comparison using statistical packages?

12. Summary
Torino section INFN active in treatment planning system research for HIT
Investigating fragmentation model of GEANT4
Comparison between TPS results using different models of ion fragmentation
Monte Carlo based treatment planning