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Making a New Turn In Matrix Metalloprotease Inhibition

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Presentation on theme: "Making a New Turn In Matrix Metalloprotease Inhibition"— Presentation transcript:

1 Making a New Turn In Matrix Metalloprotease Inhibition
Zelda R. Wasserman  Chemistry & Biology  Volume 12, Issue 2, Pages (February 2005) DOI: /j.chembiol Copyright © 2005 Elsevier Ltd Terms and Conditions

2 Figure 1 Cross-Sections through the S1′ Pockets of Four Superimposed MMP Crystal Structures The inhibitor (green) was cocrystallized with MMP-3 but could also fit the other three. The proteins are stromelysin-1 (MMP-3, pink), gelatinase A (MMP-2, beige), collagenase-3 (MMP-13, yellow), and macrophage elastase (MMP-12, cyan). Chemistry & Biology  , DOI: ( /j.chembiol ) Copyright © 2005 Elsevier Ltd Terms and Conditions

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