1. Neuromuscular electrical stimulation to improve exercise capacity in patients with severe COPD: a randomised double-blind, placebo-controlled trial 
Dr Matthew Maddocks, PhD, Claire M Nolan, MSc, William D-C Man, PhD, Prof Michael I Polkey, PhD, Nicholas Hart, PhD, Wei Gao, PhD, Gerrard F Rafferty, PhD, Prof John Moxham, MD, Prof Irene J Higginson, PhD 
The Lancet Respiratory Medicine 
Volume 4, Issue 1, Pages (January 2016)
DOI: /S (15)
Copyright © 2016 Maddocks et al. Open Access article distributed under the terms of CC BY Terms and Conditions

2. Figure 1
Trial profile
NMES=neuromuscular electrical stimulation. MRC=Medical Research Council.
The Lancet Respiratory Medicine 2016 4, 27-36DOI: ( /S (15) )
Copyright © 2016 Maddocks et al. Open Access article distributed under the terms of CC BY Terms and Conditions

3. Figure 2
Functional exercise capacity (primary outcome), quadriceps muscle strength, and mass outcomes (secondary outcomes) by treatment group
Data are mean (95% CI) change. Shaded area represents treatment period. Asterisks denote a significant between group difference of p<0·05.
The Lancet Respiratory Medicine 2016 4, 27-36DOI: ( /S (15) )
Copyright © 2016 Maddocks et al. Open Access article distributed under the terms of CC BY Terms and Conditions