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Chapter III. Structure and function of Nucleic acid

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1 Chapter III. Structure and function of Nucleic acid
1. Introduction to common properties of nucleic acid; 2. Structure and properties of DNA 3. Structure and properties of RNA

2 RNA: expression of genetic information
1) Nucleic acids are classified into two groups: DNA and RNA with different functions: DNA: storage and carrier of genetic information RNA: expression of genetic information

3 2). Both DNA and RNA are composed of nucleotides
base ribose(deoxyribose) Nucleotide= Nucleoside phosphate

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5 How to write simple formula of nucleic acids

6 1. 2. 5‘p TpApCpG-OH 3’

7 3). Nucleic acids have 260nm absorbance

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9 Phosphate group Base Sugar Purines Primidines H OH

10 Phosphodiester bond Glycosidic linkage Base Phosphate group Sugar

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