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Tunable NF-κB Oscillations in Yeast

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Presentation on theme: "Tunable NF-κB Oscillations in Yeast"— Presentation transcript:

1 Tunable NF-κB Oscillations in Yeast
Joanne M.L. Ho, Jacob R. Mattia, Matthew R. Bennett  Cell Systems  Volume 5, Issue 5, Pages (November 2017) DOI: /j.cels Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Tunable NF-κB Oscillations in Humanized Yeast
The synthetic module comprises an isolated human IκBα-RelA circuit expressed in yeast. Properties of the oscillatory waveform were controlled by tuning of the total concentration of RelA protein, strength of the negative feedback loop, and the rate of IκBα degradation. Cell Systems 2017 5, DOI: ( /j.cels ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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