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Volume 148, Issue 5, Pages e142-e147 (November 2015)

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Presentation on theme: "Volume 148, Issue 5, Pages e142-e147 (November 2015)"— Presentation transcript:

1 Volume 148, Issue 5, Pages e142-e147 (November 2015)
A 66-Year-Old Man With a Past History of Relapsing Polychondritis Presented With Right Upper Lobe Consolidation, Nodular Airway Lesions, and a Corticosteroid- Responsive Chronic Cough  Carlos D. Martínez-Balzano, MD, Andres Sosa, MD, Sean O'Reilly, MD, Yuna Gong, MD, Richard Irwin, MD, Master FCCP  CHEST  Volume 148, Issue 5, Pages e142-e147 (November 2015) DOI: /chest Copyright © 2015 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Thoracic imaging. A, Chest radiograph showing consolidation of the right upper lobe. B-D, Chest CT scan revealed right upper lobe consolidation, less extensive focal disease in the left upper lobe, and mediastinal lymphadenopathy in lung (B, C) and soft tissue (D) windows. CHEST  , e142-e147DOI: ( /chest ) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Bronchoscopic images demonstrating nodular and plaque-like confluent lesions within the airway mucosa. A, trachea. B, Left main bronchus. CHEST  , e142-e147DOI: ( /chest ) Copyright © 2015 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Histopathologic findings from transbronchial biopsies (hematoxylin and eosin stains). A, Compressed lung parenchyma with multiple eosinophilic microabscesses (black circles) (original magnification × 4). B, A higher magnification of one of the encircled regions in A, showing an aggregate of eosinophils with bright red granules; scant fibrin (pink amorphous material) surrounding the eosinophils is shown as well (original magnification × 40). C, Bronchial wall (endobronchial lesions) with diffuse, mixed inflammatory infiltrate (original magnification × 10). D, A higher magnification of C with intravascular aggregates of eosinophils (black arrow) and scattered eosinophils and plasma cells (original magnification × 40). CHEST  , e142-e147DOI: ( /chest ) Copyright © 2015 The American College of Chest Physicians Terms and Conditions


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