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Links between age at menarche, antral follicle count, and body mass index in African American and European American women  Sonya M. Schuh, Ph.D., Julia.

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Presentation on theme: "Links between age at menarche, antral follicle count, and body mass index in African American and European American women  Sonya M. Schuh, Ph.D., Julia."— Presentation transcript:

1 Links between age at menarche, antral follicle count, and body mass index in African American and European American women  Sonya M. Schuh, Ph.D., Julia Kadie, Mitchell P. Rosen, M.D., Barbara Sternfeld, Ph.D., Renee A. Reijo Pera, Ph.D., Marcelle I. Cedars, M.D.  Fertility and Sterility  Volume 111, Issue 1, Pages (January 2019) DOI: /j.fertnstert Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Associations between age at menarche, BMI, and AFC among European American (left) and African American (right) women. (A) Shown are BMI values vs. menarcheal age for European American and African American women (regression equations and R2 values are indicated). (B) The mean total AFCs for women of each BMI class, and the average age at menarche for each BMI class (shown below x-axes) are plotted for European American (left) and African American (right) women. Asterisks indicate statistically significant differences (*P<.05; **P<.005). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Association between age at menarche and mean AFC among European American and African American women. Shown are menarcheal ages vs. average total AFC for European American (A) and African American (B) women. Regression equations and R2 values are indicated. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

4 Supplemental Figure Development, maturation, and depletion of the human female oocyte pool and associated reproductive lifespan, showing candidate genes associated with menarche, menopause, and AFC. Shown in boxes are identified genes containing variants associated menarche, menopause, and AFC. These represent novel candidate genes for future ovarian and fertility studies (asterisks indicate genes associated with two or more ovarian/reproductive parameters; modified from reference 47). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions


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