Presentation is loading. Please wait.

Presentation is loading. Please wait.

David P. Mason, MD, Lillian H. Batizy, MS, Jeffrey Wu, MD, Edward R

Published byΜήδεια Γεννάδιος Modified over 5 years ago

Similar presentations

Presentation on theme: "David P. Mason, MD, Lillian H. Batizy, MS, Jeffrey Wu, MD, Edward R"— Presentation transcript:

1 Matching donor to recipient in lung transplantation: How much does size matter? 
David P. Mason, MD, Lillian H. Batizy, MS, Jeffrey Wu, MD, Edward R. Nowicki, MD, MS, Sudish C. Murthy, MD, PhD, Ann M. McNeill, RN, Marie M. Budev, DO, Atul C. Mehta, MD, Gösta B. Pettersson, MD, PhD, Eugene H. Blackstone, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 137, Issue 5, Pages e1 (May 2009) DOI: /j.jtcvs Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Distribution of differences in aTLC versus pTLC by diagnosis. PAH, Pulmonary arterial hypertension; IPF, idiopathic pulmonary fibrosis; aTLC, actual total lung capacity; pTLC, predicted total lung capacity. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Cumulative distribution of donor-to-recipient TLC according to diagnosis. A, Donor-to-recipient pTLCRatio. B, Donor-to-recipient aTLCRatio. IPF, Idiopathic pulmonary fibrosis; pTLCRatio, donor-to-recipient predicted total lung capacity ratio; aTLCRatio, donor-to-recipient actual total lung capacity ratio. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Overall unadjusted survival by terciles of donor-to-recipient pTLCRatio. Symbols represent deaths. Vertical bars represent 68% confidence limits equivalent to ± 1 standard error. Numbers in parentheses represent patients remaining at risk (P [log-rank] = .4). o = patients with largest 15% of pTLCRatio. • = patients with the middle 70% of pTLCRatio. □ = patients with the smallest 15% of pTLCRatio. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Unadjusted survival in patients with emphysema stratified by donor-to-recipient aTLCRatio. o = patients with extreme values of aTLCRatio (n = 44). □ = the 70% of patients with more typical values (n = 108). Format is as in Figure 3. P (Wilcoxon) = .01. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

6 Figure 5 Predicted mean FEV1% after lung transplantation for emphysema from multivariable model of Table 4. A, Individual curves represent specific values of donor-to-recipient pTLCRatio. B, Individual curves represent specific values of donor-to-recipient aTLCRatio. FEV1%, Forced expiratory volume in 1 second; pTLCRatio, donor-to-recipient predicted total lung capacity ratio; aTLCRatio, donor-to-recipient actual total lung capacity ratio. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

7 Figure 6 Predicted mean FEV1% after lung transplantation for IPF from multivariable model of Table 4. A, Individual curves represent specific values of donor-to-recipient pTLCRatio. B, Individual curves represent specific values of donor-to-recipient aTLCRatio. FEV1%, Forced expiratory volume in 1 second; pTLCRatio, donor-to-recipient predicted total lung capacity ratio; aTLCRatio, donor-to-recipient actual total lung capacity ratio. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

8 Figure 7 Predicted mean FEV1% after lung transplantation for bronchiectasis from multivariable model of Table 4. A, Individual curves represent specific values of donor-to-recipient pTLCRatio. B, Individual curves represent specific values of donor-to-recipient aTLCRatio. FEV1%, Forced expiratory volume in 1 second; pTLCRatio, donor-to-recipient predicted total lung capacity ratio; aTLCRatio, donor-to-recipient actual total lung capacity ratio. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

9 Number of patients with spirometry measurements available at and beyond various time points, and number of spirometry measurements available for analysis (black bars, spirometry measurements; grey bars, patients). The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

Download ppt "David P. Mason, MD, Lillian H. Batizy, MS, Jeffrey Wu, MD, Edward R"

Similar presentations

Thomas W. Rice, MD, Deepak Khuntia, MD, Lisa A. Rybicki, MS, David J

Thomas W. Rice, MD, Deepak Khuntia, MD, Lisa A. Rybicki, MS, David J
Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: The role of intrathecal papaverine 

Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: The role of intrathecal papaverine 
Influence of diabetes on survival in patients with cystic fibrosis before and after lung transplantation  Don Hayes, MD, MS, Alpa V. Patel, MD, Sylvester.

Influence of diabetes on survival in patients with cystic fibrosis before and after lung transplantation  Don Hayes, MD, MS, Alpa V. Patel, MD, Sylvester.
Two decades of pediatric lung transplant in the United States: Have we improved?  Farhan Zafar, MD, Jeffrey S. Heinle, MD, Marc G. Schecter, MD, Joseph.

Two decades of pediatric lung transplant in the United States: Have we improved?  Farhan Zafar, MD, Jeffrey S. Heinle, MD, Marc G. Schecter, MD, Joseph.
Is lung cancer resection indicated in patients with idiopathic pulmonary fibrosis?  Atsushi Watanabe, MD, PhD, Tetsuya Higami, MD, PhD, Syunsuke Ohori,

Is lung cancer resection indicated in patients with idiopathic pulmonary fibrosis?  Atsushi Watanabe, MD, PhD, Tetsuya Higami, MD, PhD, Syunsuke Ohori,
Residual patient, anatomic, and surgical obstacles in treating active left-sided infective endocarditis  Syed T. Hussain, MD, Nabin K. Shrestha, MD, Steven.

Residual patient, anatomic, and surgical obstacles in treating active left-sided infective endocarditis  Syed T. Hussain, MD, Nabin K. Shrestha, MD, Steven.
Surgical management of secondary tricuspid valve regurgitation: Annulus, commissure, or leaflet procedure?  Jose L. Navia, MD, Edward R. Nowicki, MD,

Surgical management of secondary tricuspid valve regurgitation: Annulus, commissure, or leaflet procedure?  Jose L. Navia, MD, Edward R. Nowicki, MD,
Lobar lung transplantation: One size fits all

Lobar lung transplantation: One size fits all
Prognosis of patients removed from a transplant waiting list for medical improvement: Implications for organ allocation and transplantation for status.

Prognosis of patients removed from a transplant waiting list for medical improvement: Implications for organ allocation and transplantation for status.
Mitral stenosis with pulmonary hypertension: We should operate early

Mitral stenosis with pulmonary hypertension: We should operate early
Advising complex patients who require complex heart operations

Advising complex patients who require complex heart operations
Should lung transplantation be performed for patients on mechanical respiratory support? The US experience  David P. Mason, MD, Lucy Thuita, MS, Edward.

Should lung transplantation be performed for patients on mechanical respiratory support? The US experience  David P. Mason, MD, Lucy Thuita, MS, Edward.
Siva Raja, MD, PhD, Thomas W. Rice, MD, John Ehrlinger, PhD, John R

Siva Raja, MD, PhD, Thomas W. Rice, MD, John Ehrlinger, PhD, John R
Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched.

Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched.
Lars G. Svensson, MD, PhD, Lillian H. Batizy, MS, Eugene H

Lars G. Svensson, MD, PhD, Lillian H. Batizy, MS, Eugene H
Effect of changes in postoperative spirometry on survival after lung transplantation  David P. Mason, MD, Jeevanantham Rajeswaran, MSc, Liang Li, PhD,

Effect of changes in postoperative spirometry on survival after lung transplantation  David P. Mason, MD, Jeevanantham Rajeswaran, MSc, Liang Li, PhD,
Endovascular versus open elephant trunk completion for extensive aortic disease  Eric E. Roselli, MD, Sreekumar Subramanian, MD, Zhiyuan Sun, BS, Jahanzaib.

Endovascular versus open elephant trunk completion for extensive aortic disease  Eric E. Roselli, MD, Sreekumar Subramanian, MD, Zhiyuan Sun, BS, Jahanzaib.
Lung transplantation with donation after cardiac death donors: Long-term follow-up in a single center  Nilto C. De Oliveira, MD, Satoru Osaki, MD, PhD,

Lung transplantation with donation after cardiac death donors: Long-term follow-up in a single center  Nilto C. De Oliveira, MD, Satoru Osaki, MD, PhD,
David P. Mason, MD, Jeevanantham Rajeswaran, MS, Sudish C

David P. Mason, MD, Jeevanantham Rajeswaran, MS, Sudish C
Surgical treatment of pseudoaneurysm of the thoracic aorta

Surgical treatment of pseudoaneurysm of the thoracic aorta

Similar presentations

Ads by Google