1. Sequence similarity clusters of SET domain methyltransferases.
Sequence similarity clusters of SET domain methyltransferases. All of the known and putative SET domain methyltransferases were analyzed by CLANS with reference proteins to infer substrate specificity. All human SET domain methyltransferases are in black. Reference proteins methylating only H3K4 are in red; those methylating H3K9 are in yellow; those methylating H3K36 are in blue; those methylating both H3K36 and H4K20 are in green; those methylating H3K9, H3K27, and H4K20 are in pink; and those methylating Rubisco are in purple. BLAST correlations are shown with gray lines; lighter shades of gray represent BLAST correlations closer to an E-value of 1, whereas darker shades of gray represent BLAST correlations that are closer to an E-value of 0.
Tanya C. Petrossian, and Steven G. Clarke Mol Cell Proteomics 2011;10:M
© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.